Enzyme Services to Enable Applications across Pharmaceuticals and Diagnostics, Food and Agriculture, and Beyond Today we are very pleased to announce the launch of Ginkgo Enzyme Services. Ginkgo Enzyme Services is powered by ultra high throughput screening and machine learning-guided protein design, as well as optimized proprietary bacterial and fungal host strains. Ginkgo Enzyme Services […]
Overview What are the advantages of large metagenomic enzyme libraries? And the dangers of small ones? Developing large metagenomic libraries allows us to identify top enzyme candidates for functionality as well as variants unencumbered by IP constraints. Use Ginkgo’s enzyme services to search genetic design space to find the right enzyme for your application. Project […]
Overview Optimizing a biocatalyst to decrease manufacturing costs A customer’s enzyme suffered from a non-optimal synthesis to hydrolysis ratio. Working together, Ginkgo engineered enzymes to improve the activity and specificity of the biocatalyst. The Customer’s Requirements Our customer wanted to reduce manufacturing costs by engineering an enzyme to improve specificity and activity. The customer’s original […]
Overview Enzymes are the machines of biological engineering, performing the chemical transformations of the living world. There are hundreds of thousands of enzymes that are relevant to the products we are building at Ginkgo. We use software and the foundry to search through the vast evolutionary space and discover the best enzyme for each job. […]
Overview The Foundry’s enzyme discovery, pathway assembly, and high-throughput analytical capabilities enable organism engineers to build complex metabolic pathways in microorganisms. These pathways are designed to produce cultured ingredients, break down materials, and improve performance of strains. The Challenge A leading company in the field of industrial fermentation wished to significantly decrease their reliance on […]
Overview Fermentation is prized for bringing incredible flavors to life. Whether it’s in wine or beer, cheese, kimchi, chocolate, or more. Recently, fermentation has also been used to make cultured ingredients for the flavor and fragrance industry, enabling the production of delicious, renewable, and accessible products. Many treasured flavors and fragrances are extracted from botanical […]
Overview Fermentation is one of the oldest biotechnological processes. But it’s not only for beer, kombucha, and sauerkraut. At Ginkgo, we incorporate high technology into our fermentation processes to rapidly optimize process parameters for scale up. The Challenge Working with one of our flavor and fragrance partners, we fine-tuned an existing pathway in yeast to […]
Overview When a leading pharmaceutical partner hit a roadblock in developing enzymatic solutions for their production process, Ginkgo Bioworks leveraged protein discovery and engineering to develop bio-based manufacturing. Ginkgo’s engineers developed an end-to-end work package starting from high-throughput assay development through advanced protein engineering, identifying and improving on a new class of enzymes to catalyze […]
Overview What if medicines could sense and respond to health conditions directly in your gut? Together with Synlogic, we’re programming microbes to treat complex diseases in the gut with the power of biology. The Problem Branched-chain amino acids such as leucine, isoleucine, and valine are essential amino acids that cannot be synthesized by the body. […]
Overview What if agriculture could be redesigned from the ground up? Ginkgo and Bayer have partnered to accelerate the research and development of biological products for agriculture. Together, we’re engineering plant microbes to solve growers’ greatest challenges. Nitrogen Fertilizer 5% Total worldwide natural gas used 3% Contribution to global greenhouse gas emissions Our Partnership Bayer’s […]